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Seachem Cupramine – Copper Treatment for External Parasites (100ml)


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Quick Overview

Seachem Cupramine – 100ml is a superior copper-based treatment for eradicating external parasites such as Ich, Velvet, Amyloodinium, and Cryptocaryon in both freshwater and marine aquariums. Buffered and non-acidic, it is safer than other copper medications and fully removable with carbon or CupriSorb™.



Treats Ich, Velvet, Oodinium, and other ectoparasites

Buffered, ionic copper – less toxic and more stable

Safe for fish – not safe for invertebrates

Easily removed with activated carbon or CupriSorb™


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  • Seachem Cupramine – Copper Treatment for External Parasites (100ml)

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    Seachem Cupramine – Copper-Based Parasite Treatment for Freshwater & Marine Fish (100ml)

    Seachem Cupramine is a highly effective copper treatment for external parasites in aquarium fish. It eradicates Ich (Ichthyophthirius), Velvet (Amyloodinium), Cryptocaryon, and other protozoan infections. Unlike copper sulfate or chloride, Cupramine is non-acidic, fully ionic, and remains in solution without contaminating the filter bed.

    Cupramine is safe for use in both freshwater and marine systems, but it is toxic to invertebrates and should not be used in tanks containing shrimp, snails, or corals. It is easily removed with activated carbon or Seachem CupriSorb™ after treatment.

    Key Features:

    • Eradicates Ich, Velvet, Amyloodinium, Cryptocaryon, and more
    • Buffered and non-acidic – safer than other copper treatments
    • Remains in solution – does not bind to substrate or filter media
    • Safe for fish when dosed correctly – not safe for invertebrates
    • Easily removed with carbon or CupriSorb™

    Product Specifications:

    • Brand: Seachem
    • Volume: 100ml
    • Form: Liquid (ionic copper)
    • Country of Origin: United States

    Directions for Use:

    • Remove all invertebrates before treatment
    • Turn off UV, ozone, and chemical filtration (e.g., carbon, Purigen)
    • Day 1: Add 1 mL (20 drops) per 40 L (10.5 US gallons)
    • Day 3: Repeat the same dose
    • Maintain copper concentration at 0.5 mg/L (0.25 mg/L for freshwater)
    • Use Seachem MultiTest™ Copper to monitor levels
    • Do not exceed 0.6 mg/L copper
    • Treat for 14 days at full concentration
    • After treatment, remove with carbon or CupriSorb™

    Pro Tips:

    • Visible symptoms may worsen before improving – continue full course
    • Do not use with ammonia binders or conditioners during treatment
    • Test copper levels daily to ensure therapeutic range is maintained

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